Resveratrol

I-Resveratrol yi-polyphenolic antitoxin efumaneka kwiintlobo ngeentlobo zezityalo, kubandakanywa amantongomane, amaqunube, kunye neediliya, ezifumaneka kakhulu kwingcambu ye-polygonum cuspidatum.I-Resveratrol isetyenziswe ukunyanga ukuvuvukala e-Asia kangangamakhulu eminyaka.Kwiminyaka yakutshanje, izibonelelo zezempilo zewayini ebomvu zibalelwa kubukho bayo kumdiliya.Impembelelo ivela kwisiganeko esaziwa ngokuba yiFrench Paradox.

I-Paradox yesiFrentshi yacetywa okokuqala ngugqirha wase-Ireland ogama linguSamuel Blair kwiphepha lezemfundo elapapashwa ngo-1819. AmaFrentshi ayakuthanda ukutya, atya ukutya okunekhalori ephezulu kunye ne-cholesterol, kwaye kodwa anezehlo ezisezantsi kakhulu zesifo senhliziyo kunabantu abathetha isiNgesi. abalingane.Ngoko kutheni oku kusenzeka?Ngokutsho kophando, abantu basekuhlaleni badla ngokutya newayini enetannin eninzi ukukhapha isidlo.Iwayini ebomvu iqukethe i-resveratrol, ekhusela amahlule egazi, inciphisa ukuvuvukala, ikhuthaza ukunyuswa kwemithambo yegazi kwaye inqanda ukukhula kwebhaktheriya.

I-Resveratrol yafunyanwa kwi-1924 okokuqala ngqa kwiimvavanyo zebhayoloji.Amajapan afumana iresveratrol kwiingcambu zezityalo ngo 1940. Ngo 1976, ama Britane aphinda afumana i resveratrol kwi wayini, ingafikelela ku 5-10mg/kg kudidi oluphezulu lwe wayini ebomvu eyomileyo.IResveratrol inokufumaneka kwi wayini, kuba iintsuba zediliya ezisetyenziswa ekwenzeni iwayini ziqulethe iresveratrol.Kwinkqubo yokwenza iwayini ngendlela yesiko lomsebenzi wezandla, iresveratrol ingena kwinkqubo yemveliso ye wayini ngamaxolo omdiliya, ekugqibeleni inyibilike kancinane kunye nokukhutshwa kotywala kwi wayini.Ngeminyaka yoo-1980, abantu bafumana ngokuthe ngcembe ubukho be-resveratrol kwizityalo ezininzi, ezifana nembewu ye-cassia, i-polygonum cuspidatum, i-peanut, i-mulberry kunye nezinye izityalo.

Izifundo zeBotanist zibonise ukuba i-resveratrol yendalo luhlobo lwe-antitoxin efihliweyo zizityalo ebusweni bobunzima okanye ukuhlasela kwe-pathogen.I-synthesis ye-resveratrol inyuka ngokukhawuleza xa ibonakaliswe kwimitha ye-ultraviolet, umonakalo womatshini kunye nosulelo lwefungal, ngoko kuthiwa yi-antibiotics yezityalo.I-Resveratrol inokunceda izityalo ukuba zilwe noxinzelelo lwangaphandle olunjenge-trauma, ibhaktheriya, ukusuleleka kunye nemitha ye-ultraviolet, ngoko akuninzi kakhulu ukuyibiza ngokuba ngumgcini wendalo wezityalo.

I-Resveratrol ibonakaliswe ukuba ine-antioxidant, i-anti-free radical, i-anti-tumor, i-cardiovascular protection kunye nezinye iziphumo.
I-1.I-Antioxidant, i-anti-free-radical effect-I-Resveratrol i-antioxidant yendalo, eyona nxaxheba ibalaseleyo kukukhupha okanye ukuvimbela isizukulwana sama-radicals amahhala, ukuvimbela i-lipid peroxidation, nokulawula imisebenzi ye-enzymes ehlobene ne-antioxidant.
I-2.I-Anti-tumor effect- I-anti-tumor effect ye-resveratrol ibonise ukuba inokuthintela ukuqaliswa, ukukhuthaza kunye nokuphuhliswa kwe-tumor.Iyakwazi ukuchasa umhlaza wesisu, umhlaza wamabele, umhlaza wesibindi, i-leukemia kunye nezinye iiseli zethumba ukuya ngamanqanaba ahlukeneyo ngeendlela ezahlukeneyo.
I-3.I-Cardiovascular protection- I-Resveratrol ilawula amanqanaba e-cholesterol yegazi kwaye inciphisa umngcipheko wesifo senhliziyo ngokuzibophelela kwi-estrogen receptors emzimbeni.Ngaphezu koko, i-resveratrol ikwanayo ne-anti-platelet agglutination effect, enokuthintela iiplatelet ukuba zingadityaniswa ukuze zenze amahlwili egazi abambelele eludongeni lwenqanawa, ngaloo ndlela inqanda kwaye ithomalalisa ukwenzeka kunye nophuhliso lwezifo zentliziyo.
I-4.Impembelelo ye-Estrogen- I-Resveratrol ifana nesakhiwo kwi-estrogen diethylstilbestrol, ebophelela kwi-estrogen receptors kwaye idlala indima ye-estrogen yokuguqulwa kwesignali.
I-5.I-Anti-inflammatory and antimicrobial effects- I-Resveratrol ine-inhibitory effect kwi-Staphylococcus aureus, i-catacoccus, i-Escherichia coli kunye ne-Pseudomonas aeruginosa.Izifundo zovavanyo ezichasayo zibonise ukuba i-resveratrol inokufikelela kwisiphumo sonyango ngokunciphisa ukunamathela kweplatelet kunye nokutshintsha umsebenzi weplatelet ngexesha lenkqubo yokuchasana nokuvuvukala.

Inkampani yethu isebenze kwi-resveratrol extraction iminyaka engaphezu kwe-20, inobutyebi bemveliso, uphando kunye namava ophuhliso.Isiphumo esihle sesondlo se-Resveratrol siye saxhatshazwa ngokubanzi ngabantu abohlukeneyo.Ngokusekwe kuqikelelo lweemarike, amandla okuba i-resveratrol isetyenziswe njengesongezelelo yomelele, ngakumbi kwizifo ezithile.Izongezelelo zokutya ngenye yezona ndawo zisetyenziswa kakhulu kwi-resveratrol, kwaye imboni yesiselo iye yamkeleka ngakumbi kuneshishini lokutya kwizinto ezintsha zokutya kunye neziselo, ngakumbi iziphuzo zamandla.Ukongeza, ukhetho lwabathengi kwiimveliso zendalo luya kuqhuba ukusetyenziswa ngokubanzi kwe-resveratrol kwizongezo.

Ngokwezibalo ezingaphelelanga, ukusetyenziswa kwehlabathi kwe-resveratrol kunyuke ngesantya esiphakathi sokukhula kwe-5.59%.Ukususela ngo-2015, iUnited States ithathe ipesenti ze-76.3 zeemveliso ze-resveratrol zehlabathi, ngelixa iYurophu ibala ipesenti ze-15.1 kuphela.Okwangoku, uninzi lweemveliso zesondlo se-resveratrol zivela eUnited States.Imfuno ye-resveratrol iyanda ngenxa yemfuno enkulu yeemveliso ezisezantsi.

Ngokuhambelana nombono wokuba noxanduva kuluntu, ishishini kunye nabasebenzi, i-Uniwell biotechnology isoloko incamathele ukubaluleka okukhulu kulawulo lwenkqubo yokuvelisa kunye nokuhlolwa komgangatho weemveliso.Ukusuka ekuthengeni izinto ezikrwada, ukuveliswa, ukupakishwa, ukuthengisa kunye nenkonzo emva kokuthengisa, sithobela ngokungqongqo iimfuno ze-GMP zolawulo.Sineqela eliqinisekisa umgangatho owomeleleyo, izixhobo zokuhlola eziphambili (HPLC, GC, njl.) inkqubo yolawulo lomgangatho ongqongqo.

Sixhasa iofisi esebenzayo, ezibophelele ekwakheni ishishini lokuvelisa isityalo esisebenzayo, ukubonelela ngemveliso yendalo, ekumgangatho ophezulu wesityalo sokutya, iimveliso zempilo, izithambiso, amayeza kunye namanye amashishini.