Ulwazi olusisiseko:
Igama leMveliso: I-Bitter Almond Extract Molecular formula: C20H27NO11
I-solvent Extraction: I-Ethanol kunye namanzi Ubunzima bemolekyuli: 457.42
Ilizwe leMvelaphi: I-China Irradiation: I-non-radiated
Ukuchongwa: TLC GMO: Non-GMO
Umthwali/AbaThumeli: Akukho HS KHOWUDI: 1302199099
I-Amygdalin ifumaneka ikakhulu kwiapilkosi, ialmond, ipesika, inectarine, loquat, iplamu, iapile, icherry emnyama kunye namanye amandongomane kunye namagqabi.I-Amygdalin ayikho eluswini lwe-amygdalin.
Umsebenzi:
1. umphumo we-amygdalin kwi-cardiovascular
2. umphumo we-amygdalin kwinkqubo yokugaya
1) Anti gastric ulcer: iziphumo ze-amygdalin kwisilonda sesisu sokulinga zabonwa ngokuseka imodeli yeempuku ezibotshelelwe ngumkhenkce isilonda sesisu, imodeli yesilonda esitshisayo i-acetic kunye nemodeli yesilonda sesisu seempuku se-ligation yepylorus.Iziphumo zibonise ukuba iqela le-20 kunye ne-40 mg / kg ye-amygdalin inokuthintela ukunyanzeliswa kwengcinezelo yokukhenkceza kwesilonda sesisu kwiigundane;5. Amaqela e-10 kunye ne-20 mg / kg anokukhuthaza ukuphiliswa kwesilonda;10. Indawo yesilonda yesilonda esiswini esibangelwa yi-pylorus ligation yancitshiswa kwi-20 mg / kg yeqela, ebonisa ukuba i-amygdalin inesiphumo esingcono sokulwa nesilonda.
2) I-Fibrosis yesibindi: imodeli ye-bleomycin yasekwa yindlela yokuvezwa kwe-tracheal.I-Amygdalin i-15 mg / kg ifakwe kwi-intraperitoneally ukuphanda umphumo wayo kwi-expression ye-collagen I kunye ne-III kwiigundane ze-bleomycin.Ngomhla we-7, i-14 kunye ne-28 yeentsuku ze-modeling, ipesenti yendawo ye-collagen yohlobo lwe-III kwiqela le-amygdalin yayingaphantsi kuneqela le-bleomycin, kwaye ipesenti yohlobo lwe-collagen indawo kwi-lung tissue ye-amygdalin yehla ngosuku lwe-28.Kwacetyiswa ukuba i-amygdalin inokuthintela ukwakheka kwe-collagen I kunye ne-III, kwaye icothise ngokufanelekileyo inkqubo ye-pulmonary fibrosis kwiigundane zokulinga, iphakamisa ukuba iyeza linokusetyenziswa kuthintelo kunye nonyango lwe-pulmonary fibrosis yabantu.
3. Umphumo we-amygdalin kwinkqubo ye-urinary: imodeli ye-renal interstitial fibrosis yasungulwa ngokuphazamiseka kwe-ureter ye-unilateral.Iigundane zanikwa i-3, i-5 mg / D nge-gavage kwiqela le-amygdalin, kwaye izilwanyana zabulawa iintsuku ze-7,14,21 emva kokusebenza, kwaye umonakalo we-pathological of kidneys kwiqela ngalinye wabonwa.Iziphumo zabonisa ukuba iqondo le-renal fibrosis yeqela le-amygdalin lalisezantsi kakhulu kunelo leqela le-unilateral ureteral obstruction ngeentsuku ezingama-21, apho iqela lonyango le-3 mg / D lehla nge-35%, kwaye iqela lonyango le-5mg / D lehla. ngama-28%.Kwaboniswa ukuba i-amygdalin inokunciphisa ngokucacileyo iqondo lomonakalo we-renal pathological kunye nokulibazisa inkqubo ye-renal interstitial fibrosis, kwaye ibonise ngakumbi ukuba i-amygdalin ine-anti fibrosis effect;
4. umphumo we-amygdalin kwi-immune system
5. Impembelelo ye-ntitumor ye-amygdalin: i-1.25 ukuya kwi-10g / L i-amygdalin kwiiseli zomhlaza wesinyi (UMUC-3, RT112, TCCSUP) ngamaxesha e-3 ngeveki, iiveki ze-2 kamva zafumanisa ukuba i-amygdalin i-dose ixhomekeke ekukhulisweni kwe-tumor cell kunye nokuzala, ukwenzela ukuba stagnate kwisigaba G0/G1, kunye 10 g/L xa isiphumo best.Ukufuduka kunye nekhono lokunamathisela i-mumuc-3 kunye ne-RT112 yehla kakhulu phantsi kwesenzo se-10 g / L amygdalin, kodwa amandla okufuduka kwe-tccsup anyukile, ebonisa ukuba i-amygdalin inokulawula i-integrin β 1 okanye β 4, ichaphazela isinamathiselo kunye nokufuduka. yeeseli zomhlaza wesinyi, kwaye umphumo wayo unxulumene nohlobo lweseli.
6. umphumo we-amygdalin kwinkqubo yokuphefumula
Iinkcukacha zokupakisha:
Ukupakisha kwangaphakathi: Ingxowa ye-PE ephindwe kabini
Ukupakisha kwangaphandle: Igubu (igubu lephepha okanye igubu lentsimbi yentsimbi)
Ixesha lokuhambisa: Kwiintsuku ezisi-7 emva kokufumana intlawulo
Udinga umenzi wezityalo oqeqeshiweyo, sisebenze kule ntsimi kwiminyaka engama-20 kwaye sinophando olunzulu kuyo.
Imveliso yezempilo, izongezo zokutya, izithambiso
